Penicillin Cocktail Recipe: Easy Steps & Tips to Perfect It

Penicillin Cocktail Recipe: Easy Steps & Tips to Perfect It cocktail

Who doesn’t love a drink that’s sweet, smoky, and just the right amount of tangy? The Penicillin cocktail is a modern favorite that combines Scotch whisky, honey, ginger, and lemon into a perfectly balanced sip. It’s one of those drinks that feels both comforting and sophisticated—great for a cozy evening or impressing friends at a dinner party. I’ve made this cocktail countless times, and it never fails to hit the spot. Let’s walk through how to make it, step by step, so you can enjoy this gem at home.

Penicillin cocktail

Penicillin

Base

Scotch

Alcohol

20%

Prep Time

5 minutes

Calories

215 kcal

Carbs

14g

Fat

0g

Ingredients

You’ll need just a handful of ingredients to whip up this crowd-pleaser. Here’s the list:

  • 2 oz (60 ml) blended Scotch whisky
  • 1/4 oz (7.5 ml) single malt Scotch (for that smoky finish)
  • 3/4 oz (22 ml) fresh lemon juice
  • 3/4 oz (22 ml) honey-ginger syrup
  • Candied ginger (for garnish)

Equipment needed: A rocks glass (or Old Fashioned glass), a cocktail shaker, and a fine strainer.

Prep Time & Servings

  • Prep time: 5 minutes
  • Servings: 1 cocktail

Method

  1. Add 2 oz of blended Scotch whisky, 3/4 oz of fresh lemon juice, and 3/4 oz of honey-ginger syrup to a cocktail shaker filled with ice.
  2. Shake vigorously for about 15 seconds until the mixture is well chilled. You’ll know it’s ready when the shaker feels icy cold to the touch.
  3. Strain the mixture into a rocks glass filled with fresh ice.
  4. Using the back of a spoon, gently pour 1/4 oz of single malt Scotch over the top to create a “float.” This adds that signature smoky aroma and taste.
  5. Garnish with a piece of candied ginger on the rim or skewered for presentation.

Tip: If you don’t have candied ginger, a thin lemon slice or even a small piece of fresh ginger works beautifully.

Honey-Ginger Syrup

Making the syrup from scratch is easy and totally worth it. Here’s how:

  • Combine 1/2 cup (120 ml) honey, 1/2 cup (120 ml) water, and 1-inch piece of fresh ginger (sliced) in a small saucepan.
  • Bring to a gentle simmer and stir until the honey dissolves.
  • Let it cool, then strain out the ginger. Store in the fridge for up to a week.

Shortcut: If you’re short on time, store-bought ginger syrup mixed with honey will also work.

Storage Tips

If you’re making the honey-ginger syrup ahead, keep it in a clean jar or bottle in the refrigerator. It’ll stay fresh for about a week. Unfortunately, the cocktail itself is best enjoyed fresh—no leftovers here!

Serving Suggestions

I love serving Penicillins at casual gatherings or as a post-dinner treat. The drink pairs beautifully with food. Here are a few pairing ideas:

  • Grilled meats: The smoky Scotch mirrors the charred flavors of grilled steak or chicken.
  • Aged cheese platter: The sweet honey and tangy lemon cut through the richness of cheeses like sharp cheddar or gouda.
  • Dark chocolate desserts: The citrusy brightness of the cocktail balances the richness of chocolate.

Tips for Success

  • Use fresh lemon juice: It makes all the difference in the cocktail’s brightness and balance. Bottled lemon juice just doesn’t compare.
  • Choose your Scotch wisely: A blended Scotch provides a smooth base, while the single malt float adds that signature smoky kick. If you’re not into smoky flavors, you can skip the float.
  • Adjust the sweetness: If you prefer a less sweet drink, reduce the honey in the syrup slightly or add more lemon juice.

Variations to Try

If you’re feeling adventurous, here are a few ways to switch things up:

Smoky Joe

  • Replace the blended Scotch with mezcal for an extra smoky, earthy twist.

Honey Bee

  • Swap the Scotch for bourbon and add a dash of orange bitters. The result is a slightly sweeter, warmer take on the original.

Spiced Penicillin

  • Infuse your honey-ginger syrup with a cinnamon stick or a few cloves for a spiced-up version.

Virgin Penicillin

  • For a non-alcoholic option, use a smoky tea like Lapsang Souchong in place of the Scotch. Adjust the honey and lemon to taste.

FAQs

What makes the Penicillin cocktail special?

It’s all about balance. The smoky Scotch, zingy ginger, sweet honey, and tart lemon come together in perfect harmony, creating a drink that’s comforting yet complex.

Can I use any Scotch I have on hand?

Yes! While the recipe calls for both blended and single malt Scotch, you can use whatever you have. Just know that the smoky single malt adds a lot to the drink’s character.

How do I make it less sweet?

Reduce the honey in the syrup or add an extra splash of lemon juice to brighten things up.

Is this drink really “healing”?

While it’s not medicine, the honey and ginger do have soothing properties, and the lemon adds a nice dose of vitamin C. But remember, it’s still a cocktail—drink responsibly!

Can I batch this for a party?

You can pre-mix the Scotch, lemon juice, and honey-ginger syrup in a pitcher, then shake with ice and strain into glasses just before serving. Keep the single malt float for the final touch.


The Penicillin has been a personal favorite of mine for years. It’s one of those cocktails that feels like a little bit of magic in a glass—warm, smoky, and just sweet enough. Whether you’re making it for yourself or serving it to friends, I hope you enjoy this modern classic as much as I do!

Jake Morrison avatar
Jake Morrison
3 days ago